Article
Expression of P0- and P3-RNA from the normal and translocated c-myc allele in Burkitt's lymphoma cells.
Oncogene - 1 Sept 1990
Eick D, Polack A, Kofler E, Lenoir G M, Rickinson A B, Bornkamm G W
Abstract excerpt
We have studied the allele specific expression of c-myc P0- and P3-RNA in Burkitt's lymphoma (BL) cells. The steady state levels of P0-RNA show considerable variations in BL cells. Expression of P0-RNA was found to be restricted to the translocated allele, but could be induced by TPA from the nor...
Topics
- Alleles
- Amino Acid Sequence
- Burkitt Lymphoma
- Cycloheximide
- Gene Expression Regulation, Neoplastic
- Genes, myc
- Humans
- Molecular Sequence Data
- Promoter Regions, Genetic
- RNA, Neoplasm
- Tetradecanoylphorbol Acetate
- Transcription, Genetic
- Translocation, Genetic
