Back to search

Article

Morphology and gene expression profiling provide complementary information for mapping cell state

2021-10-22

Abstract excerpt

<h4>Summary</h4> Morphological and gene expression profiling can cost-effectively capture thousands of features in thousands of samples across perturbations by disease, mutation, or drug treatments, but it is unclear to what extent the two modalities capture overlapping versus complementary information. Here, using both the L1000 and Cell Painting assays to profile gene expression and cell morphology, respectivel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0026d90a-ce2b-5660-958b-f4ca03c29b1c
DOI
10.1101/2021.10.21.465335
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Morphology and gene expression profiling provide complementary information for mapping cell stateDOI 10.1101/2021.10.21.465335
Select a neighboring publication to make it the new centre.