Article

Influenza A infection accelerates disease-associated microglia formation during physiological aging

2025-12-14

Abstract excerpt

Severe pneumonia is associated with an increased risk of cognitive decline and dementia, particularly in the elderly. Changes in microglia, the most abundant immune cell population in the brain, are also associated with cognitive decline and dementia, including the emergence of a transcriptional cell state referred to as disease-associated microglia (DAM). We sought to test the hypothesis that non-neuroinvasive in...

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Literature Corpus work: ac60122e-de2b-586f-92f3-c184beead0a5
DOI: 10.64898/2025.12.11.693336

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