Article

Age-specific activation of microglial genes in a mouse model of AD

2022-10-30

Abstract excerpt

<h4>ABSTRACT</h4> Alzheimer’s disease (AD) is a neurodegenerative disease that increases its prevalence with age. AD is characterized by a progressive loss of cognitive function, leading to dementia. The conventional pathological hallmarks of AD include deposition of amyloid plaque, aggregation of neurofibrillary tangles, and sustained inflammation. Recent studies have confirmed that immune responses play an impo...

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Literature Corpus work: 845d67c3-c602-5060-bf66-ee877b5356da
DOI: 10.1101/2022.10.28.514172

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