Article

Multi-modal single cell analysis reveals brain immune landscape plasticity during aging and gut microbiota dysbiosis

2020-07-16

Abstract excerpt

<h4>ABSTRACT</h4> The brain contains a diverse array of immune cell types. The phenotypic and functional plasticity of brain immune cells collectively contribute to brain tissue homeostasis and disease progression. Immune cell plasticity is profoundly influenced by local tissue microenvironment cues and systemic factors. Yet, the transcriptional mechanism by which systemic stimuli, such as aging and gut microbiot...

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Literature Corpus work: afc66f8d-992e-5bca-9905-ff84dcd0f52f
DOI: 10.1101/2020.07.15.205377

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