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The Human Microglia Atlas (HuMicA) Unravels Changes in Homeostatic and Disease-Associated Microglia Subsets across Neurodegenerative Conditions

2023-08-14

Abstract excerpt

<title>Abstract</title> <p>Dysregulated microglia activation, leading to neuroinflammation, is crucial in neurodegenerative disease development and progression. The initial M1/M2 dual activation classification for microglia is outdated. Even the ‘disease-associated microglia’ (DAM) phenotype, firstly described in mice, falls short in representing the diverse microglia phenotypes in pathology. In this study, we ha...

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Literature Corpus work
88a62d52-50e6-515e-94ab-e32147b64aba
DOI
10.21203/rs.3.rs-3227213/v1
Open publication

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The Human Microglia Atlas (HuMicA) Unravels Changes in Homeostatic and Disease-Associated Microglia Subsets across Neurodegenerative ConditionsDOI 10.21203/rs.3.rs-3227213/v1
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