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Genome-wide binding of Multiple ankyrin repeats single KH domain reveals its role in maintenance of gene activation by trithorax group proteins in <i>Drosophila</i>

2022-03-16

Abstract excerpt

The Trithorax group (trxG) proteins counteract repressive effect of Polycomb group (PcG) complexes and maintain transcriptional memory of active states of key developmental genes. Although, chromatin structure and modifications appear to play a fundamental role in this process, it is not clear how trxG prevents PcG-silencing and heritably maintain an active gene expression state. Here, we report a hitherto unknown...

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Literature Corpus work
ac2d9494-e9a2-56f6-aad2-e07e4be01891
DOI
10.1101/2022.03.15.484481
Open publication

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Genome-wide binding of Multiple ankyrin repeats single KH domain reveals its role in maintenance of gene activation by trithorax group proteins in <i>Drosophila</i>DOI 10.1101/2022.03.15.484481
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