Article
Antagonizing Polycomb group-mediated gene repression by chromatin remodelers.
Epigenetics - 1 Jan 2010
Köhler Claudia, Aichinger Ernst
Abstract excerpt
Cellular identity is maintained by epigenetic processes that prevent changes of cell-type specific transcriptional programs. Polycomb group (PcG) proteins are evolutionary conserved key players of cellular identity that repress central developmental regulators by modifying chromatin structure. PcG-mediated repression is antagonized by trithorax group (trxG) proteins that prevent inappropriate repression by PcG...
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