Article
Polycomb group targeting through different binding partners of RING1B C-terminal domain.
Structure (London, England : 1993) - 11 Aug 2010
Wang Renjing, Taylor Alexander B, Leal Belinda Z, Chadwell Linda V, Ilangovan Udayar, Robinson Angela K, Schirf Virgil, Hart P John, Lafer Eileen M, Demeler Borries, Hinck Andrew P, McEwen Donald G, Kim Chongwoo A
Abstract excerpt
RING1B, a Polycomb Group (PcG) protein, binds methylated chromatin through its association with another PcG protein called Polycomb (Pc). However, RING1B can associate with nonmethylated chromatin suggesting an alternate mechanism for RING1B interaction with chromatin. Here, we demonstrate that t...
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