Article
The RING1 subunit of Polycomb Repressive Complex 1 monoubiquitinates histone H2A and mediates repression independently of Polycomb Repressive Complex 2 in the model diatom Phaeodactylum tricornutum.
The New phytologist - 1 Mar 2026
Wu Yue, Zhao Xue, Chen Jing Xuan, Chaumier Timothée, Tirichine Leïla
Abstract excerpt
Polycomb Repressive Complex 1 (PRC1) and its associated mark, H2A monoubiquitination (H2Aub), cooperate with PRC2 for transcriptional silencing in multicellular organisms. However, PRC1 is absent from many unicellular lineages, leaving its functional conservation and relationship with PRC2 unclear. In the model diatom Phaeodactylum tricornutum, the role of the PRC1 subunit RING1 was investigated to assess whether...
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