Article

Intact and Degenerate Diguanylate Cyclases regulate <i>Shigella</i> Cyclic di-GMP

2024-04-08

Abstract excerpt

The intracellular human pathogen Shigella invades the colonic epithelium to cause disease. Prior to invasion, this bacterium navigates through different environments within the human body, including the stomach and the small intestine. To adapt to changing environments, Shigella uses the bacterial second messenger c-di-GMP signaling system, synthesized by diguanylate cyclases (DGCs) encoding GGDEF domains. Shig...

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Literature Corpus work: abdc963c-c750-55c7-95ff-60539f7d5c98
DOI: 10.1101/2024.04.08.588579

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