Article

Shigella's c-di-GMP specific PDEs Modulate Biofilm and Virulence Phenotypes

2026-06-23

Abstract excerpt

To establish infection and cause disease, the intracellular pathogen Shigella must successfully navigate a series of host defenses and distinct microenvironments within the human body. One way Shigella navigates these environments is by using the secondary messenger c-di-GMP, which regulates many different bacterial behaviours. C-di-GMP is synthesized by diguanylate cyclases (DGCs) and broken down by c-di-GMP sp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5fde68ab-47ff-5981-8f87-a90c304ec90d
DOI: 10.64898/2026.06.22.733758

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Shigella's c-di-GMP specific PDEs Modulate Biofilm and Virulence PhenotypesDOI 10.64898/2026.06.22.733758Read

Shigella flexneri Diguanylate Cyclases Regulate Virulence.Semantic proximity Read

Intact and mutated Shigella diguanylate cyclases increase c-di-GMP.Semantic proximity Read

Intact and Degenerate Diguanylate Cyclases regulate <i>Shigella</i> Cyclic di-GMPSemantic proximity Read

c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and PhosphodiesterasesSemantic proximity Read

The Bacterial Second Messenger Cyclic di-GMP Regulates Brucella Pathogenesis and Leads to Altered Host Immune Response.Semantic proximity Read

Detailed analysis of c-di-GMP mediated regulation of csgD expression in Salmonella typhimurium.Semantic proximity Read

Cyclic diguanylate riboswitches control bacterial pathogenesis mechanismsSemantic proximity Read

Quantitative input-output dynamics of a c-di-GMP signal-transduction cascade in <i>Vibrio cholerae</i>Semantic proximity Read

Comparative analysis of diguanylate cyclase and phosphodiesterase genes in Klebsiella pneumoniae.Semantic proximity Read

Systematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in Dickeya zeae EC1.Semantic proximity Read

Differential control of Yersinia pestis biofilm formation in vitro and in the flea vector by two c-di-GMP diguanylate cyclases.Semantic proximity Read

Prevailing concepts of c-di-GMP signaling.Semantic proximity Read