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Article

The Bacterial Second Messenger Cyclic di-GMP Regulates Brucella Pathogenesis and Leads to Altered Host Immune Response.

Infection and immunity - 1 Dec 2016

Khan Mike, Harms Jerome S, Marim Fernanda M, Armon Leah, Hall Cherisse L, Liu Yi-Ping, Banai Menachem, Oliveira Sergio C, Splitter Gary A, Smith Judith A

Abstract excerpt

Brucella species are facultative intracellular bacteria that cause brucellosis, a chronic debilitating disease significantly impacting global health and prosperity. Much remains to be learned about how Brucella spp. succeed in sabotaging immune host cells and how Brucella spp. respond to environmental challenges. Multiple types of bacteria employ the prokaryotic second messenger cyclic di-GMP (c-di-GMP) to...

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Identifiers

PMID: 27672085
DOI: 10.1128/IAI.00531-16
PMCID: PMC5116723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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