Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cyclic diguanylate differentially regulates the expression of virulence factors and pathogenesis-related phenotypes in Clostridioides difficile.

Microbiological research - 1 Sept 2024

Ouyang Zirou, Zhao Min, Li Jiayiren, Zhang Yulian, Zhao Jianhong

Abstract excerpt

Clostridioides difficile infection (CDI) caused by toxigenic C. difficile is the leading cause of antimicrobial and healthcare-associated diarrhea. The pathogenicity of C. difficile relies on the synergistic effect of multiple virulence factors, including spores, flagella, type IV pili (T4P), toxins, and biofilm. Spores enable survival and transmission of C. difficile, while adhesion factors such as flagella and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Toxins
Share to Biofilms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Clostridioides difficile

Share to Clostridium Infections

Share to Cyclic GMP

Share to Enterotoxins

Share to Flagella

Share to Spores, Bacterial

Source

Identifiers

PMID: 38909416
DOI: 10.1016/j.micres.2024.127811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cyclic diguanylate differentially regulates the expression of virulence factors and pathogenesis-related phenotypes in Clostridioides difficile.PMID 38909416Read ↗

Cyclic-di-GMP signaling in the Gram-positive pathogen Clostridium difficile.Semantic proximity Read ↗

Cyclic Diguanylate Inversely Regulates Motility and Aggregation in Clostridium difficileSemantic proximity Read ↗

c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and PhosphodiesterasesSemantic proximity Read ↗

Cyclic diguanylate riboswitches control bacterial pathogenesis mechanismsSemantic proximity Read ↗

c-di-GMP inhibits early sporulation in <i>Clostridioides difficile</i>Semantic proximity Read ↗

Type IV pili are involved in phenotypes associated with Clostridioides difficile pathogenesis.Semantic proximity Read ↗

Cyclic Diguanylate Regulates Virulence Factor Genes via Multiple Riboswitches in Clostridium difficileSemantic proximity Read ↗

The Second Messenger Cyclic Di-GMP Regulates Clostridium difficile Toxin Production by Controlling Expression of <i>sigD</i>Semantic proximity Read ↗

An Update on Clostridioides difficile Binary ToxinSemantic proximity Read ↗

Biofilm regulation in Clostridioides difficile: Novel systems linked to hypervirulenceSemantic proximity Read ↗

Glucosyltransferase-dependent and independent effects of <i>Clostridioides difficile</i> toxins during infectionSemantic proximity Read ↗

Shigella flexneri Diguanylate Cyclases Regulate Virulence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.