Article
Cyclic diguanylate riboswitches control bacterial pathogenesis mechanisms
7 Feb 2019
Abstract excerpt
Many bacterial species use cyclic diguanylate (c-di-GMP) to control their physiology and behaviors in response to extracellular stimuli.C-di-GMP primarily mediates the switch between a free-living, motile state and a nonmotile lifestyle, with the latter often entailing surface adherence and biofilm development [1,2].This paradigm is conserved across diverse gram-positive and gram-negative species, though the...
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