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Article

Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella.

Proceedings of the National Academy of Sciences of the United States of America - 12 May 2009

Solano Cristina, García Begoña, Latasa Cristina, Toledo-Arana Alejandro, Zorraquino Violeta, Valle Jaione, Casals Joan, Pedroso Enrique, Lasa Iñigo

Abstract excerpt

Bacteria have developed an exclusive signal transduction system involving multiple diguanylate cyclase and phosphodiesterase domain-containing proteins (GGDEF and EAL/HD-GYP, respectively) that modulate the levels of the same diffusible molecule, 3'-5'-cyclic diguanylic acid (c-di-GMP), to transmit signals and obtain specific cellular responses. Current knowledge about c-di-GMP signaling has been inferred mainly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19416883
DOI: 10.1073/pnas.0812573106
PMCID: PMC2683120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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