Article

c-di-GMP inhibits early sporulation in <i>Clostridioides difficile</i>

2021-06-25

Abstract excerpt

<h4>ABSTRACT</h4> The formation of dormant spores is essential for the anaerobic pathogen Clostridioides difficile to survive outside of the host gastrointestinal tract. The regulatory pathways and environmental signals that initiate C. difficile spore formation within the host are not well understood. One bacterial second messenger signaling molecule, cyclic diguanylate (c-di-GMP), modulates several physiologi...

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Literature Corpus work: 0742007b-c5d6-5551-b636-d7fd368bea97
DOI: 10.1101/2021.06.24.449855

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