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Vangl2 regulates the dynamics of Wnt cytonemes in vertebrates

2020-12-23

Abstract excerpt

The Wnt signalling network regulates cell proliferation and cell differentiation as well as migration and polarity in development of multicellular organisms. However, it is still unclear how distribution of Wnt ligands is precisely controlled to fulfil all of these different functions. Here, we show that the four-pass transmembrane protein Vangl2 occupies a central role in determining the distribution of Wnt by cy...

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Literature Corpus work
aba18d01-81da-5bad-ab2e-9f883cf4c0ed
DOI
10.1101/2020.12.23.424142
Open publication

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Vangl2 regulates the dynamics of Wnt cytonemes in vertebratesDOI 10.1101/2020.12.23.424142
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