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Article

An expanding role of Vangl proteins in embryonic development.

Current topics in developmental biology - 1 Jan 2012

Torban Elena, Iliescu Alexandra, Gros Philippe

Abstract excerpt

The mammalian Vangl1 and Vangl2 genes were discovered a decade ago through their association with neural tube defects, in particular the presence of Vangl2 mutations in independent alleles of the mouse mutant Loop-tail (Lp), a mouse model of the severe neural tube defect craniorachischisis. Vangl1 and Vangl2 variants have also been detected in familial and sporadic cases of spina bifida. Vangl proteins are highly...

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PMID: 23140632
DOI: 10.1016/B978-0-12-394592-1.00005-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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