Article
Planar cell polarity signalling couples cell division and morphogenesis during neurulation.
Nature - 12 Jan 2006
Ciruna Brian, Jenny Andreas, Lee Diana, Mlodzik Marek, Schier Alexander F
Abstract excerpt
Environmental and genetic aberrations lead to neural tube closure defects (NTDs) in 1 out of every 1,000 births. Mouse and frog models for these birth defects have indicated that Van Gogh-like 2 (Vangl2, also known as Strabismus) and other components of planar cell polarity (PCP) signalling might...
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