Article
A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulation.
Development (Cambridge, England) - 15 Jul 2015
Roszko Isabelle, S Sepich Diane, Jessen Jason R, Chandrasekhar Anand, Solnica-Krezel Lilianna
Abstract excerpt
During vertebrate gastrulation, convergence and extension movements elongate embryonic tissues anteroposteriorly and narrow them mediolaterally. Planar cell polarity (PCP) signaling is essential for mediolateral cell elongation underlying these movements, but how this polarity arises is poorly understood. We analyzed the elongation, orientation and migration behaviors of lateral mesodermal cells undergoing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.