Article

Macrophage differentiation is marked by increased abundance of the mRNA 3’ end processing machinery, altered poly(A) site usage, and sensitivity to the level of CstF64

2022-08-07

Abstract excerpt

Regulation of mRNA polyadenylation is important for response to external signals and differentiation in several cell types, and results in mRNA isoforms that vary in the amount of coding sequence or 3’ UTR regulatory elements. However, its role in differentiation of monocytes to macrophages has not been investigated. Macrophages are key effectors of the innate immune system that help control infection and promote...

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Literature Corpus work: ab100c6a-6a5a-5b3c-bb59-1e94bd285d56
DOI: 10.1101/2022.08.07.503082

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