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Primary human myoblasts display only minor alternative polyadenylation compared to the transformed C <sub>2</sub> C <sub>12</sub> model of muscle differentiation

2023-12-18

Abstract excerpt

Alternative polyadenylation has been linked to multiple developmental and disease transitions. The prevailing hypothesis being that differentiated cells use longer 3’ UTRs with expended regulatory capacity whereas undifferentiated cells use shorter 3’ UTRs. Here, we describe the gene expression and alternative polyadenylation profiles of human primary myoblasts over a time course of differentiation. Contrary to ex...

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Literature Corpus work
5a344031-fc88-5aa6-88fc-9ea2a91746a0
DOI
10.1101/2023.12.17.572066
Open publication

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Primary human myoblasts display only minor alternative polyadenylation compared to the transformed C <sub>2</sub> C <sub>12</sub> model of muscle differentiationDOI 10.1101/2023.12.17.572066
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