Article

CFIm25-Dependent Alternative Polyadenylation in AKT2 mRNA Programs Macrophage Polarization

2025-06-24

Abstract excerpt

<h4>Summary</h4> Macrophage polarization is essential for immune responses, tissue homeostasis, and progression of many diseases. It is a tightly regulated process involving an intricate network of signaling pathways and control mechanisms at the level of transcription, alternative mRNA splicing, translation and mRNA stability. However, regulation through alternative mRNA polyadenylation (APA), remains poorly und...

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Literature Corpus work: d44861ea-74c6-5a66-85b2-1ac139263e86
DOI: 10.1101/2025.06.19.660629

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