Article

Acetylcholine Hydrolytic Activity of Fibrillated β-Amyloid (1-40) Peptide

2023-06-30

Abstract excerpt

Alzheimer's disease is characterized by the presence of senile plaques composed of β-amyloid peptide (Aβ) aggregates with toxic effects that are still not fully understood. Recently, it was discovered that Aβ(1-42) fibrils possess catalytic activity on acetylcholine hydrolysis. Catalytic amyloids are an emerging and exciting field of research. In this study, we examined the catalytic activity of the fibrils formed...

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Literature Corpus work: aaafd5d8-b704-5a96-bb0d-cdc9b08b4c5b
DOI: 10.21203/rs.3.rs-3117304/v1

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