Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Betaine suppressed Aβ generation by altering amyloid precursor protein processing.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Jul 2014

Liu Xiu-Ping, Qian Xiang, Xie Yue, Qi Yan, Peng Min-Feng, Zhan Bi-Cui, Lou Zheng-Qing

Abstract excerpt

Betaine was an endogenous catabolite of choline, which could be isolated from vegetables and marine products. Betaine could promote the metabolism of homocysteine in healthy subjects and was used for hyperlipidemia, coronary atherosclerosis, and fatty liver in clinic. Recent findings shown that B...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Peptides
Share to Amyloid beta-Protein Precursor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amyloid Precursor Protein Secretases

Share to Betaine

Share to Chromatography, High Pressure Liquid

Share to Homocysteine

Share to L-Lactate Dehydrogenase

Share to Neuroblastoma

Source

Identifiers

PMID: 24549986
DOI: 10.1007/s10072-014-1630-y

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24549986-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Betaine suppressed Aβ generation by altering amyloid precursor protein processing.PMID 24549986Read ↗

Natural compounds that modulate BACE1-processing of amyloid-beta precursor protein in Alzheimer's disease.Semantic proximity Read ↗

Lycopene attenuates Aβ1-42 secretion and its toxicity in human cell and Caenorhabditis elegans models of Alzheimer disease.Semantic proximity Read ↗

BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's diseaseSemantic proximity Read ↗

Association between Dietary Choline and Betaine Intake and 10.6-Year Cardiovascular Disease Outcomes and Mortality in AdultsSemantic proximity Read ↗

Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity.Semantic proximity Read ↗

In Vitro and In Vivo Neuroprotective Effects of SarcosineSemantic proximity Read ↗

Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease.Semantic proximity Read ↗

Inhibitory effects of curcumin on H2O2-induced cell damage and APP expression and processing in SH-SY5Y cells transfected with APP gene with Swedish mutation.Semantic proximity Read ↗

A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humansSemantic proximity Read ↗

Salvianolic Acid B Inhibits Aβ Generation by Modulating BACE1 Activity in SH-SY5Y-APPsw CellsSemantic proximity Read ↗

Nutrients and polyphenols-rich Sorghum bicolor genotypes as complementary therapy for Alzheimer’s diseaseSemantic proximity Read ↗

Effects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.