Article

Three distinct velocities of elongating RNA polymerase define exons and introns

2016-03-17

Abstract excerpt

<h4>ABSTRACT</h4> Differential elongation rates of RNA polymerase II (RNAP) have been posited to be a critical determinant for pre-mRNA splicing. Molecular dissection of mechanisms coupling transcription elongation rate with splicing requires knowledge of instantaneous RNAP elongation velocity at exon and introns. However, only average RNAP elongation rates over large genomic distances can be inferred with curren...

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Literature Corpus work: aaa40081-c3c5-5e5b-91ef-823ad09bece6
DOI: 10.1101/044123

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