Article

Quantifying RNA Synthesis at Rate-Limiting Steps of Transcription Using Nascent RNA-Sequencing Data

2021-08-05

Abstract excerpt

<h4>Summary</h4> Nascent RNA-sequencing tracks transcription at nucleotide resolution. The genomic distribution of engaged transcription complexes, in turn, uncovers functional genomic regions. Here, we provide data-analytical steps to 1) identify transcribed regulatory elements de novo genome-wide, 2) quantify engaged transcription complexes at enhancers, promoter-proximal regions, divergent transcripts, gene b...

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Literature Corpus work: 26679f70-6a3d-5095-b45f-4c2ccefb8894
DOI: 10.1101/2021.08.03.454856

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