Article

Genome-wide Cross-multi-trait Analysis into Shared Genetic Architecture of Coronary Artery Disease and Aortic Aneurysms

2025-06-28

Abstract excerpt

<h4>ABSTRACT</h4> While affecting distinct vascular territories, coronary artery disease, abdominal aortic aneurysms and thoracic aortic aneurysms share similar risk factors and pathophysiological resemblance. To identify novel pleiotropic and heterogenous loci, we performed a joint meta-analysis leveraging the shared genetic architecture of thereof. Using summary statistics from three independent genome-wide asso...

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Literature Corpus work: aa83e80d-d113-502d-bea9-538324d4df98
DOI: 10.1101/2025.06.27.25330395

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