Article

Shared Genetic Architecture Contributes to Risk of Major Cardiovascular Diseases

2023-09-18

Abstract excerpt

<title>Abstract</title> <p>The extensive co-occurrence of cardiovascular diseases (CVDs), as evidenced by epidemiological studies, aligns with positive genetic correlations identified in comprehensive genetic investigations. However, the precise nature and mechanisms governing these multifaceted effects remain elusive. By assessing genome-wide and local genetic correlations, polygenic overlaps, and causal connect...

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Literature Corpus work: b242e199-44a1-5c44-a6e9-dfa80afe7fe9
DOI: 10.21203/rs.3.rs-3261702/v1

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