Article

Shared Genetic Susceptibility between Abdominal Aortic Aneurysm and Cardiometabolic Traits

2023-12-08

Abstract excerpt

Abdominal aortic aneurysm (AAA) presents abnormal metabolism and co-occurs with cardiometabolic disorders, suggesting a shared genetic susceptibility. We investigated this commonality leveraging recent GWAS studies of AAA and 32 cardiometabolic traits (CMTs). Significant genetic correlations are found between AAA and 21 CMTs, among which are causal relationship with coronary artery disease, hypertension, lipid tra...

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Literature Corpus work: 2383e59b-64c1-5d20-88c7-117ffdf8b86a
DOI: 10.1101/2023.12.05.23299523

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