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Article

Shared genetic etiology of vessel diseases: A genome-wide multi-traits association analysis.

Thrombosis research - 1 Sept 2024

Song Jiangwei, Gao Ning, Chen Zhe, Xu Guocong, Kong Minjian, Wei Dongdong, Sun Qi, Dong Aiqiang

Abstract excerpt

BACKGROUND: The comorbidity among vascular diseases has been widely reported, however, the contribution of shared genetic components remains ambiguous. METHODS: Based on genome-wide association study summary statistics, we employed statistical genetics methodologies to explore the shared genetic basis of eight vascular diseases: coronary artery disease, abdominal aortic aneurysm, ischemic stroke, peripheral...

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PMID: 39059088
DOI: 10.1016/j.thromres.2024.109102

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