Article
Common and distinct genetic features of three atherosclerotic cardiovascular diseases.
Atherosclerosis - 1 May 2026
Li Ling, Malik Rainer, Abrahamian Carla, von Scheidt Moritz, Chen Zhifen, Kessler Thorsten, Dichgans Martin, Schunkert Heribert
Abstract excerpt
BACKGROUND AND AIMS: Coronary artery disease (CAD), peripheral arterial disease (PAD), and ischemic stroke (IS) are the principal manifestations of atherosclerotic cardiovascular diseases (ASCVDs). Here we systematically explored the shared and distinct genetic underpinnings of these ASCVDs. METHODS: SNP-based heritability estimates were calculated using GCTA-GREML in a subset of the UK Biobank, where 8000...
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