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Article

Abdominal aortic aneurysm and cardiometabolic traits share strong genetic susceptibility to lipid metabolism and inflammation.

Nature communications - 5 Jul 2024

Zheng Shufen, Tsao Philip S, Pan Cuiping

Abstract excerpt

Abdominal aortic aneurysm has a high heritability and often co-occurs with other cardiometabolic disorders, suggesting shared genetic susceptibility. We investigate this commonality leveraging recent GWAS studies of abdominal aortic aneurysm and 32 cardiometabolic traits. We find significant genetic correlations between abdominal aortic aneurysm and 21 of the cardiometabolic traits investigated, including causal...

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Share to Aortic Aneurysm, Abdominal
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Hypertension

Share to Inflammation

Share to Lipid Metabolism

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 38969659
DOI: 10.1038/s41467-024-49921-7
PMCID: PMC11226445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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