Article
Genome-wide association studies of cardiovascular disease.
Physiological reviews - 1 Jul 2023
Walsh Roddy, Jurgens Sean J, Erdmann Jeanette, Bezzina Connie R
Abstract excerpt
Genome-wide association studies (GWAS) aim to identify common genetic variants that are associated with traits and diseases. Since 2005, more than 5,000 GWAS have been published for almost as many traits. These studies have offered insights into the loci and genes underlying phenotypic traits, have highlighted genetic correlations across traits and diseases, and are beginning to demonstrate clinical utility by...
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