Article

Clinical Significance of TP53, PAX5, and JAK2 gene mutation in Pediatric Acute Lymphoblastic Leukemia

2023-08-29

Abstract excerpt

<h4>Background: </h4> Pediatric acute lymphoblastic leukemia (ALL) is the most common childhood cancer worldwide. Developed countries have a 90% 5-year overall survival rate with proper treatment, while LMICs have a poor rate of around 30-50%. AIM: The research aims to identify mutations in frequently mutated genes’ hotspot regions to design appropriate treatment plans based on patients’ somatic makeup. <h4>Method...

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Literature Corpus work: aa59f10b-cd68-5bc3-9f28-71a7b52f45b2
DOI: 10.22541/au.169330511.17703003/v1

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