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[Mutation and expression of PAX5 gene in adult acute lymphoblastic leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Oct 2014

Lin Zhong-Kun, Zhang Run, Ge Zheng, Xu Jing-Yan, Liu Juan, Guo Xing, Li Min, Wu Yu-Jie, Qiao Chun, Qiu Hai-Rong, Zhang Jian-Fu, Li Jian-Yong

Abstract excerpt

PAX5 is an important transcription factor of paired-box(PAX) family. The aim of this study was to investigate the mutations and expression of PAX5 and its clinical significance in adult patients with acute lymphoblastic leukemia (ALL). Reverse transcription polymerase chain reaction (RT-PCR) and genomic PCR were performed to detect the deletions of PAX5 and point mutations of PAX5 exon 2-10 in 101 cases of adult...

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Identifiers

PMID: 25338558
DOI: 10.7534/j.issn.1009-2137.2014.05.003

Genes

PAX5

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