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Article

[Spectrum of somatic mutations and their prognostic significance in adult patients with B cell acute lymphoblastic leukemia].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Feb 2018

Feng J, Gong X Y, Jia Y J, Liu K Q, Li Y, Dong X B, Fang Q Y, Ru K, Li Q H, Wang H J, Zhao X L, Jia Y N, Song Y, Tian Z, Wang M, Tang K J, Wang J X, Mi Y C

Abstract excerpt

Objective: To investigate the spectrum of gene mutations in adult patients with B-acute lymphoblastic leukemia (B-ALL), and to analyze the influences of different gene mutations on prognosis. Methods: DNA samples from 113 adult B-ALL patients who administered from June 2009 to September 2015 were collected. Target-specific next generation sequencing (NGS) approach was used to analyze the mutations of 112 genes...

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Share to B-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29562441
DOI: 10.3760/cma.j.issn.0253-2727.2018.02.004
PMCID: PMC7342576

Genes

PTPN11
FAT1
MPL
JAK1
JAK2
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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