Article

Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemia

2022-09-23

Abstract excerpt

<h4>Purpose: </h4> The 5-year survival rate of children with acute lymphoblastic leukemia (ALL) is 85–90%, with a 10–15% rate of treatment failure. Next-generation sequencing (NGS) identified recurrent mutated genes in ALL that might alter the diagnosis, classification, prognostic stratification, treatment, and response to ALL. Few studies on gene mutations in Chinese pediatric ALL have been identified. Thus, an i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4d910da3-5b79-5842-b5d6-626264c672cf
DOI: 10.21203/rs.3.rs-2020888/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemiaDOI 10.21203/rs.3.rs-2020888/v1Read

Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemia.Semantic proximity Read

Spectrum and Clinical Characteristics of Gene Mutations in Chinese Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read

Spectrum and clinical characteristics relevance of gene mutations in Chinese pediatric acute lymphoblastic leukemiaSemantic proximity Read

Genetic mutational analysis of pediatric acute lymphoblastic leukemia from a single center in China using exon sequencingSemantic proximity Read

Characteristics of Molecular Genetic Mutations and Their Correlation with Prognosis in Adolescent and Adult Patients with Acute Lymphoblastic Leukemia.Semantic proximity Read

Genomic heterogeneity contributed to different prognosis between adult and pediatric acute lymphoblastic.Semantic proximity Read

Genomic Heterogeneity Contributed To The Different Survival Between Adult and Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read

[Clinical Study on the Relationship between Gene Mutation Profile and Prognosis in Pediatric Acute Lymphocyte Leukemia].Semantic proximity Read

The RAS-signaling-pathway-mutation-related prognosis in B-cell acute lymphoblastic leukemia: A report from South China children's leukemia group.Semantic proximity Read

Genomic and Clinical Analysis of Children with Acute Lymphoblastic Leukemia.Semantic proximity Read

[Mutational spectrum and its prognostic significance in childhood acute lymphoblastic leukemia based on next-generation sequencing technology].Semantic proximity Read

Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.Semantic proximity Read