Article
Characteristics of Molecular Genetic Mutations and Their Correlation with Prognosis in Adolescent and Adult Patients with Acute Lymphoblastic Leukemia.
Oncology - 1 Jan 2024
Sun Xue, Liu Xiaoqian, Li Ying, Shi Xue, Li Yahan, Tan Ran, Jiang Yujie, Sui Xiaohui, Ge Xueling, Xu Hongzhi, Wang Xin, Fang Xiaosheng
Abstract excerpt
INTRODUCTION: The prognosis of acute lymphoblastic leukemia (ALL) in adolescents and adults is poor, and recurrence is an important cause of their death. Changes of genetic information play a vital role in the pathogenesis and recurrence of ALL; however, the impact of molecular genetic mutations on disease diagnosis and prognosis remains unexplored. This study aimed to explore the frequency spectrum of gene...
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