Article

Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

2023-01-24

Abstract excerpt

<h4>ABSTRACT</h4> Patient-derived xenograft (PDX) models involve the engraftment of tumour tissue in immunocompromised mice and represent an important pre-clinixtcal oncology research. A limitation of non-small cell lung cancer (NSCLC) PDX model derivation in NOD- scid IL2Rgamma null (NSG) mice is that a subset of initial engraftments are of lymphocytic, rather than tumour origin. In the lung TRACERx PDX pipeli...

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Literature Corpus work: a9bf693a-12b3-5d8f-b17f-01bf50bbd1db
DOI: 10.1101/2023.01.24.520089

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