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Article

Spatial distribution of tertiary lymphoid structures in the molecular and clinical context of non-small cell lung cancer.

Cellular oncology (Dordrecht, Netherlands) - 1 Jun 2025

Elfving Hedvig, Yu Hui, Fessehatsion Kaleab Kassete, Brunnström Hans, Botling Johan, Gulyas Miklos, Backman Max, Lindberg Amanda, Strell Carina, Micke Patrick

Abstract excerpt

INTRODUCTION: Tertiary lymphoid structures (TLS) are lymphocyte aggregates resembling secondary lymphoid organs and are pivotal in cancer immunity. The ambiguous morphological definition of TLS makes it challenging to ascertain their clinical impact on patient survival and response to immunotherapy. OBJECTIVES: This study aimed to characterize TLS in hematoxylin-eosin tissue sections from lung cancer patients,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40029549
DOI: 10.1007/s13402-025-01052-x
PMCID: PMC12119696

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FOXP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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