Article

A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis

2022-10-27

Abstract excerpt

Patient-derived xenografts (PDXs) model human intra-tumoral heterogeneity in the context of the intact tissue of immunocompromised mice. Histological imaging via hematoxylin and eosin (H&E) staining is performed on PDX samples for routine assessment and, in principle, captures the complex interplay between tumor and stromal cells. Deep learning (DL)-based analysis of large human H&E image repositories has extract...

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Literature Corpus work: 11fbd9bf-7b18-5a72-813f-1e21413a8d5f
DOI: 10.1101/2022.10.26.512745

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