Article

Transcription factor regulation of eQTL activity across individuals and tissues

2021-07-20

Abstract excerpt

Tens of thousands of genetic variants associated with gene expression ( cis -eQTLs) have been discovered in the human population. These eQTLs are active in various tissues and contexts, but the molecular mechanisms of eQTL variability are poorly understood, hindering our understanding of genetic regulation across biological contexts. Since many eQTLs are believed to act by altering transcription factor (TF) bindi...

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Literature Corpus work: a37654a1-8c13-5b67-9a31-aa4771c3a2fe
DOI: 10.1101/2021.07.20.453075

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