Article
Predicting genotype-specific gene regulatory networks.
Genome research - 1 Mar 2022
Weighill Deborah, Ben Guebila Marouen, Glass Kimberly, Quackenbush John, Platig John
Abstract excerpt
Understanding how each person's unique genotype influences their individual patterns of gene regulation has the potential to improve our understanding of human health and development, and to refine genotype-specific disease risk assessments and treatments. However, the effects of genetic variants are not typically considered when constructing gene regulatory networks, despite the fact that many disease-associated...
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