Article

Identification of the molecular components of enhancer-mediated gene expression variation in multiple tissues regulating blood pressure

2023-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Inter-individual variation in blood pressure (BP) arises in part from sequence variants within numerous enhancers modulating expression of an unknown number of causal genes. We propose that these genes are active in tissues relevant to BP physiology and can be identified from tissue epigenomic data and genotypes of BP-phenotyped individuals. We used the ENCODE project’s H3K27ac and ATAC-seq data...

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Literature Corpus work: dc02b246-539b-595b-bc69-01ca9166b088
DOI: 10.1101/2023.12.07.23299084

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