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Article

Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks

2024-11-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> Imaging-based, single-cell spatial transcriptomics (iSCST) using formalin-fixed, paraffin-embedded (FFPE) tissue could transform translational research by retaining all tissue cell subsets and spatial locations while enabling the analysis of archived specimens. We aimed to develop a robust framework for applying iSCST to archived clinical FFPE mucosal biopsies from pa...

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Literature Corpus work
c131b187-fa24-5588-961f-d38346f2457f
DOI
10.1101/2024.11.11.623014
Open publication

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Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networksDOI 10.1101/2024.11.11.623014
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