Article

Characterization of transcript enrichment and detection bias in single-nuclei RNA-seq for mapping of distinct human adipocyte lineages

2021-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell RNA-sequencing (scRNA-seq) enables molecular characterization of complex biological tissues at high resolution. The requirement of single-cell extraction, however, makes it challenging for profiling tissues such as adipose tissue where collection of intact single adipocytes is complicated by their fragile nature. For such tissues, single-nuclei extraction is often much more efficient...

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Literature Corpus work: 7b8bacc1-5b42-576f-8674-e3280e97ea17
DOI: 10.1101/2021.03.24.435852

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