Article

Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney

2020-06-15

Abstract excerpt

The integration of single cell transcriptome and chromatin accessibility datasets enables a deeper understanding of cell heterogeneity. We performed single nucleus ATAC (snATAC-seq) and RNA (snRNA-seq) sequencing to generate paired, cell-type-specific chromatin accessibility and transcriptional profiles of the adult human kidney. We demonstrate that snATAC-seq is comparable to snRNA-seq in the assignment of cell i...

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Literature Corpus work: 23ffc0b4-7a7b-50c5-a19b-15277f2e85f4
DOI: 10.1101/2020.06.14.151167

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