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Generation of prostate cancer assembloids modeling the patient-specific tumor microenvironment

31 Mar 2025

Abstract excerpt

Prostate cancer (PC) is the most frequently diagnosed malignancy among men and contributes significantly to cancer-related mortality. While recent advances in in vitro PC modeling systems have been made, there remains a lack of robust preclinical models that faithfully recapitulate the genetic and phenotypic characteristics across various PC subtypes-from localized PC (LPC) to castration-resistant PC (CRPC)-along...

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PMID: 40163511
DOI: 10.1371/journal.pgen.1011652

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